BDS INSIGHTS by Dr Manish Khazane

I was fit and healthy when I first felt pain in a molar. After numerous dentists and doctors left it untreated, there were knock-on effects throughout my body. Today I am in constant pain and look almost unrecognisable Keren Levy Wed 20 Apr 2022 10.00 BST In 2019 I was fitter than at any other point in my life – and I had a life I loved. It was my third year at the BBC. Every day at New Broadcasting House, I knew that I was seeing world events from a rare vantage point. I loved being surrounded by all the TV monitors and feeling at the centre of things. It had its trials, like any job, but it never stopped feeling like a privilege. Alongside my work, I was an open-water swimmer and had just topped 20 years of swims between islands and across lakes and rivers with an outing in the Galápagos. In the past I’d climbed Kilimanjaro, raced across the Hellespont in Turkey and along the Thames. I swam between the Cyclades in Greece every autumn and loved the Aegean with a passion. I relis...

  Compulsory Covid jabs ‘calamitous’ for dental services in England, says BDA Thousands of dental staff will quit with ‘devastating consequences’ for patients, says dentists’ association Coronavirus – latest updates See all our coronavirus coverage Dental services are ‘already stretched to breaking point’ before the vaccine mandate for healthcare staff comes into effect, the BDA has said.  Photograph: Victoria Jones/PA Andrew Gregory  Health editor Fri 17 Dec 2021 00.01 GMT Dentists’ leaders have said mandatory jabs for healthcare staff will have a “calamitous” impact on dental services in England, as a survey revealed that one in 10 dentists have not been double-vaccinated. MPs voted this week to approve regulations requiring  NHS  and social care staff to be vaccinated by April next year. All frontline health and care staff must be fully jabbed with two Covid-19 vaccines before 1 April or risk losing their jobs. But the British Dental Association (BDA) said co...

  Periodontal disease is a biofilm-induced chronic inflammatory condition that affects the tooth-supporting tissues, which in its severe form may lead to tooth loss and negatively affect systemic health. Although host immune and inflammatory responses are crucial in the control of this biofilm, their persistence and dysregulation may lead to destruction of periodontal tissues, where neutrophils and macrophages might play an important role. Moreover, it has been shown that periodontitis is associated with several chronic inflammatory diseases, among which inflammatory bowel disease has raised special attention . Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the gastrointestinal tract, which comprises two main forms, Crohn’s disease and ulcerative colitis .  The pathogenesis of IBD involves genetic and environmental factors, such as diet, smoking, stress, and microorganisms , and it is characterized by intestinal inflammation and epithelial injury . Cro...

        Understand the problem, give it a thought ..and act accordingly to find a solution towards it.. This holds very much true in case of the recent  pandemic COVID-19.What started off as a unusual respiratory  infection, in late 2019 reported from Wuhan,China..has come on to affect 2,627,630 to date. The source of the infection identified as a novel coronavirus has emerged related to Severe Acute Respiratory Syndrome ( SARS ).                                                                                  Similar to other coronaviruses, SARS-CoV-2 particles have a spherical structure and have proteins which have spike like structure protruding from their surfaces. Mechanism of action involves the protein spike like structures attach...

The Nobel Prize in physiology or medicine was awarded Monday to three physician-scientists from the United States and Britain - William G. Kaelin Jr., Peter J. Ratcliffe and Gregg L. Semenza - "for their discoveries of how cells sense and adapt to oxygen availability. "The discoveries by the trio illuminated what the Nobel Committee called "one of life's most essential adaptive processes," answering profound questions about how the body works and providing potential new therapeutic avenues to treat cancer and other diseases. The three scientists, working independently, revealed the cascade of molecular events that allow cells to detect and respond to different levels of oxygen. That allows the human body to adapt to thinner air at high altitude by generating more red blood cells to carry oxygen. But it can also go awry in disease, providing new targets for treatment: Cancer cells exploit these molecular switches to thrive, for example, and i...