Question of the day

A 52-year-old female presents with heat intolerance, increased appetite, diarrhea, and weight loss. He has a history of hepatitis C, and is currently on ribavirin and interferon-alfa. On examination, there is a non-tender swelling on the front of his neck that moves with swallowing. On eye examination, there is no exophthalmos, ophthalmoplegia, lid lag, or chemosis. Labs reveal elevated total T3 and T4 levels, low TSH level, decreased radioiodine uptake, and increased serum thyroglobulin levels. Which of the following is the most appropriate next step in the management of this patient?

A. Treatment with a beta-blocker
B. Treatment with propylthiouracil
C. Treatment with NSAIDs
D. Treatment with prednisolone
E. Treatment with radioiodine

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